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TUORC Publications


Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study. Ding M, Huang T, Bergholdt H, Nordestgaard B, Ellervik C, and Qi L. on behalf of the CHARGE Consortium. BMJ 2017

Adherence to Healthy Lifestyle and Cardiovascular Diseases in the Chinese Population. Lv J, Yu C, Guo Y, Bian Z, Yang L, Chen Y, Tang X, Zhang W, Qian Y, Huang Y, Wang X, Chen J, Chen Z, Qi L, Li L; China Kadoorie Biobank Collaborative Group..J Am Coll Cardiol. 2017 Mar 7;69(9):1116-1125. doi: 10.1016/j.jacc.2016.11.076.

A history of Asthma from childhood and Left Ventricular Mass in asymptomatic Young Adults: the Bogalusa Heart Study. Sun D, Wang T, Heianza Y, Lv J, Han L, Rabito F, Kelly T, Li S, He J, Bazzano L, Chen W, and Qi L. JACC Heart Failure 2017

Dietary Protein Modifies the Effect of the MC4R Genotype on 2-Year Changes in Appetite and Food Craving: The POUNDS Lost Trial. Huang T, Zheng Y, Hruby A, Williamson DA, Bray GA, Shen Y, Sacks FM, Qi L.J Nutr. 2017 Mar;147(3):439-444. doi: 10.3945/jn.116.242958.

Thyroid hormones and changes in body weight and metabolic parameters in response to weight-loss diets: The POUNDS LOST trial. Liu G, Liang L, Bray GA, Qi L, Hu FB, Rood J, Sacks FM, Sun Q. Int J Obes (Lond). 2017 Jan 31. doi: 10.1038/ijo.2017.28. [Epub ahead of print]

Physical Activity, TV Watching Time, Sleeping, and Risk of Obesity and Hyperglycemia in the Offspring of Mothers with Gestational Diabetes Mellitus. Zhang T, Wang P, Liu H, Wang L, Li W, Leng J, Li N, Zhang S, Qi L, Tuomilehto J, Yu Z, Yang X, Hu G.Sci Rep. 2017 Jan 25;7:41115. doi: 10.1038/srep41115.

Multigenerational Cardiometabolic Risk as a Predictor of Birth Outcomes: The Bogalusa Heart Study. Harville EW, Jacobs MB, Qi L, Chen W, Bazzano LA.J Pediatr. 2017 Feb;181:154-162.e1. doi: 10.1016/j.jpeds.2016.10.031.


Lifestyle Cardiovascular Risk Score, Genetic Risk Score, and Myocardial Infarction in Hispanic/Latino Adults Living in Costa Rica. Sotos-Prieto M, Baylin A, Campos H, Qi L, Mattei J.J Am Heart Assoc. 2016 Dec 20;5(12). pii: e004067. doi: 10.1161/JAHA.116.004067.

Genetic variations of circulating adiponectin levels modulate changes in appetite in response to weight-loss diets. Ma W, Huang T, Heianza Y, Wang T, Sun D, Tong J, Williamson DA, Bray GA, Sacks FM, Qi L. J Clin Endocrinol Metab. 2016 Nov 14:jc20162909. [Epub ahead of print]

FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials. Livingstone KM, Celis-Morales C, Papandonatos GD, Erar B, Florez JC, Jablonski KA, Razquin C, Marti A, Heianza Y, Huang T, Sacks FM, Svendstrup M, Sui X, Church TS, Jääskeläinen T, Lindström J, Tuomilehto J, Uusitupa M, Rankinen T, Saris WH, Hansen T, Pedersen O, Astrup A, Sørensen TI, Qi L, Bray GA, Martinez-Gonzalez MA, Martinez JA, Franks PW, McCaffery JM, Lara J, Mathers JC.BMJ. 2016 Sep 20;354:i4707. doi: 10.1136/bmj.i4707.

Zinc-Associated Variant in SLC30A8 Gene Interacts With Gestational Weight Gain on Postpartum Glycemic Changes: A Longitudinal Study in Women With Prior Gestational Diabetes Mellitus. Wang T, Liu H, Wang L, Huang T, Li W, Zheng Y, Heianza Y, Sun D, Leng J, Zhang S, Li N, Hu G, Qi L.Diabetes. 2016 Dec;65(12):3786-3793.

Associations of Bowel Movement Frequency with Risk of Cardiovascular Disease and Mortality among US Women. Ma W, Li Y, Heianza Y, Staller KD, Chan AT, Rimm EB, Rexrode KM, Qi L.Sci Rep. 2016 Sep 6;6:33005. doi: 10.1038/srep33005.

Macronutrient Intake-Associated FGF21 Genotype Modifies Effects of Weight-Loss Diets on 2-Year Changes of Central Adiposity and Body Composition: The POUNDS Lost Trial. Heianza Y, Ma W, Huang T, Wang T, Zheng Y, Smith SR, Bray GA, Sacks FM, Qi L.Diabetes Care. 2016 Nov;39(11):1909-1914.

Gallstones and Risk of Coronary Heart Disease: Prospective Analysis of 270 000 Men and Women From 3 US Cohorts and Meta-Analysis. Zheng Y, Xu M, Li Y, Hruby A, Rimm EB, Hu FB, Wirth J, Albert CM, Rexrode KM, Manson JE, Qi L.Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1997-2003. doi: 10.1161/ATVBAHA.116.307507.

Plasma Taurine, Diabetes Genetic Predisposition, and Changes of Insulin Sensitivity in Response to Weight-Loss Diets. Zheng Y, Ceglarek U, Huang T, Wang T, Heianza Y, Ma W, Bray GA, Thiery J, Sacks FM, Qi L.J Clin Endocrinol Metab. 2016 Oct;101(10):3820-3826.

Two-year changes in circulating adiponectin, ectopic fat distribution and body composition in response to weight-loss diets: the POUNDS Lost Trial. Ma W, Huang T, Wang M, Zheng Y, Wang T, Heianza Y, Sun D, Smith SR, Bray GA, Sacks FM, Qi L.Int J Obes (Lond). 2016 Nov;40(11):1723-1729. doi: 10.1038/ijo.2016.128.

Determinants and Consequences of Obesity. Hruby A, Manson JE, Qi L, Malik VS, Rimm EB, Sun Q, Willett WC, Hu FB.Am J Public Health. 2016 Sep;106(9):1656-62. doi: 10.2105/AJPH.2016.303326.

Diet, Lifestyle, Biomarkers, Genetic Factors, and Risk of Cardiovascular Disease in the Nurses' Health Studies. Yu E, Rimm E, Qi L, Rexrode K, Albert CM, Sun Q, Willett WC, Hu FB, Manson JE.Am J Public Health. 2016 Sep;106(9):1616-23. doi: 10.2105/AJPH.2016.303316.

Temporal Relationship Between Childhood Body Mass Index and Insulin and Its Impact on Adult Hypertension: The Bogalusa Heart Study. Zhang T, Zhang H, Li Y, Sun D, Li S, Fernandez C, Qi L, Harville E, Bazzano L, He J, Xue F, Chen W.Hypertension. 2016 Sep;68(3):818-23. doi: 10.1161/HYPERTENSIONAHA.116.07991.

Cumulative consumption of branched-chain amino acids and incidence of type 2 diabetes. Zheng Y, Li Y, Qi Q, Hruby A, Manson JE, Willett WC, Wolpin BM, Hu FB, Qi L.Int J Epidemiol. 2016 Oct;45(5):1482-1492.

Low birthweight and risk of type 2 diabetes: a Mendelian randomisation study. Wang T, Huang T, Li Y, Zheng Y, Manson JE, Hu FB, Qi L.Diabetologia. 2016 Sep;59(9):1920-7. doi: 10.1007/s00125-016-4019-z.

Genetic predisposition to obesity is associated with insulin secretion in Chinese adults: The Cardiometabolic Risk in Chinese (CRC) study. Liang J, Sun Y, Liu X, Zhu Y, Pei Y, Wang Y, Qiu Q, Yang M, Qi L.J Diabetes Complications. 2016 Sep-Oct;30(7):1229-33. doi: 10.1016/j.jdiacomp.2016.06.006.

Genetic susceptibility to diabetes and long-term improvement of insulin resistance and β cell function during weight loss: the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial. Huang T, Ley SH, Zheng Y, Wang T, Bray GA, Sacks FM, Qi L.Am J Clin Nutr. 2016 Jul;104(1):198-204. doi: 10.3945/ajcn.115.121186.

Dietary phosphatidylcholine and risk of all-cause and cardiovascular-specific mortality among US women and men. Zheng Y, Li Y, Rimm EB, Hu FB, Albert CM, Rexrode KM, Manson JE, Qi L.Am J Clin Nutr. 2016 Jul;104(1):173-80. doi: 10.3945/ajcn.116.131771.

Genetic variation of fasting glucose and changes in glycemia in response to 2-year weight-loss diet intervention: the POUNDS LOST trial. Wang T, Huang T, Zheng Y, Rood J, Bray GA, Sacks FM, Qi L. Int J Obes (Lond). 2016 Mar 22.

Type 2 Diabetes, Diabetes Genetic Score and Risk of Decreased Renal Function and Albuminuria: A Mendelian Randomization Study. Xu M, Bi Y, Huang Y, Xie L, Hao M, Zhao Z, Xu Y, Lu J, Chen Y, Sun Y, Qi L, Wang W, Ning G. EBioMedicine. 2016 Apr;6:162-70.

Gestational hypertension and chronic hypertension on the risk of diabetes among gestational diabetes women. Yuan X, Liu H, Wang L, Zhang S, Zhang C, Leng J, Dong L, Lv L, Lv F, Tian H, Qi L, Tuomilehto J, Hu G. J Diabetes Complications. 2016 May 4.

Weight-Loss Diets, Adiponectin, and Changes in Cardiometabolic Risk in the 2-Year POUNDS Lost Trial. Ma W, Huang T, Zheng Y, Wang M, Bray GA, Sacks FM, Qi L. J Clin Endocrinol Metab. 2016 Jun;101(6):2415-22.

Ready-to-Eat Cereal Consumption with Total and Cause-Specific Mortality: Prospective Analysis of 367,442 Individuals. Xu M, Huang T, Lee AW, Qi L, Cho S. J Am Coll Nutr. 2016 Apr;35(3):217-23.

Sugar-sweetened beverage intake, chromosome 9p21 variants, and risk of myocardial infarction in Hispanics. Zheng Y, Li Y, Huang T, Cheng HL, Campos H, Qi L. Am J Clin Nutr. 2016 Mar 9. pii: ajcn107177

Diabetes and Risk of Arterial Stiffness: A Mendelian Randomization Analysis. Xu M, Huang Y, Xie L, Peng K, Ding L, Lin L, Wang P, Hao M, Chen Y, Sun Y, Qi L, Wang W, Ning G, Bi Y. Diabetes. 2016 Jun;65(6):1731-40.

Weight-loss diets and 2-y changes in circulating amino acids in 2 randomized intervention trials. Zheng Y, Ceglarek U, Huang T, Li L, Rood J, Ryan DH, Bray GA, Sacks FM, Schwarzfuchs D, Thiery J, Shai I, Qi L. Am J Clin Nutr. 2016 Feb;103(2):505-11.

Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans. Li M, Wu DD, Yao YG, Huo YX, Liu JW, Su B, Chasman DI, Chu AY, Huang T, Qi L, Zheng Y; CHARGE Nutrition Working Group; DietGen Consortium, Luo XJ. Schizophr Bull. 2016 Jan;42(1):178-90

Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Wen W, Kato N, Hwang JY, Guo X, Tabara Y, Li H, Dorajoo R, Yang X, Tsai FJ, Li S, Wu Y, Wu T, Kim S, Guo X, Liang J, Shungin D, Adair LS, Akiyama K, Allison M, Cai Q, Chang LC, Chen CH, Chen YT, Cho YS, Choi BY, Gao Y, Go MJ, Gu D, Han BG, He M, Hixson JE, Hu Y, Huang T, Isono M, Jung KJ, Kang D, Kim YJ, Kita Y, Lee J, Lee NR, Lee J, Wang Y, Liu JJ, Long J, Moon S, Nakamura Y, Nakatochi M, Ohnaka K, Rao D, Shi J, Sull JW, Tan A, Ueshima H, Wu C, Xiang YB, Yamamoto K, Yao J, Ye X, Yokota M, Zhang X, Zheng Y, Qi L, Rotter JI, Jee SH, Lin D, Mohlke KL, He J, Mo Z, Wu JY, Tai ES, Lin X, Miki T, Kim BJ, Takeuchi F, Zheng W, Shu XO. Sci Rep. 2016 Jan 20;6:17958


Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, Rayner NW, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M, Strawbridge RJ, Kestler H, Chheda H, Eisele L, Gustafsson S, Steinthorsdottir V, Thorleifsson G, Qi L, Karssen LC, van Leeuwen EM, Willems SM, Li M, Chen H, Fuchsberger C, Kwan P, Ma C, Linderman M, Lu Y, Thomsen SK, Rundle JK, Beer NL, van de Bunt M, Chalisey A, Kang HM, Voight BF, Abecasis GR, Almgren P, Baldassarre D, Balkau B, Benediktsson R, Blüher M, Boeing H, Bonnycastle LL, Bottinger EP, Burtt NP, Carey J, Charpentier G, Chines PS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Doney AS, Dorkhan M, Edkins S, Eriksson JG, Esko T, Eury E, Fadista J, Flannick J, Fontanillas P, Fox C, Franks PW, Gertow K, Gieger C, Gigante B, Gottesman O, Grant GB, Grarup N, Groves CJ, Hassinen M, Have CT, Herder C, Holmen OL, Hreidarsson AB, Humphries SE, Hunter DJ, Jackson AU, Jonsson A, Jørgensen ME, Jørgensen T, Kao WH, Kerrison ND, Kinnunen L, Klopp N, Kong A, Kovacs P, Kraft P, Kravic J, Langford C, Leander K, Liang L, Lichtner P, Lindgren CM, Lindholm E, Linneberg A, Liu CT, Lobbens S, Luan J, Lyssenko V, Männistö S, McLeod O, Meyer J, Mihailov E, Mirza G, Mühleisen TW, Müller-Nurasyid M, Navarro C, Nöthen MM, Oskolkov NN, Owen KR, Palli D, Pechlivanis S, Peltonen L, Perry JR, Platou CG, Roden M, Ruderfer D, Rybin D, van der Schouw YT, Sennblad B, Sigurðsson G, Stančáková A, Steinbach G, Storm P, Strauch K, Stringham HM, Sun Q, Thorand B, Tikkanen E, Tonjes A, Trakalo J, Tremoli E, Tuomi T, Wennauer R, Wiltshire S, Wood AR, Zeggini E, Dunham I, Birney E, Pasquali L, Ferrer J, Loos RJ, Dupuis J, Florez JC, Boerwinkle E, Pankow JS, van Duijn C, Sijbrands E, Meigs JB, Hu FB, Thorsteinsdottir U, Stefansson K, Lakka TA, Rauramaa R, Stumvoll M, Pedersen NL, Lind L, Keinanen-Kiukaanniemi SM, Korpi-Hyövälti E, Saaristo TE, Saltevo J, Kuusisto J, Laakso M, Metspalu A, Erbel R, Jöcke KH, Moebus S, Ripatti S, Salomaa V, Ingelsson E, Boehm BO, Bergman RN, Collins FS, Mohlke KL, Koistinen H, Tuomilehto J, Hveem K, Njølstad I, Deloukas P, Donnelly PJ, Frayling TM, Hattersley AT, de Faire U, Hamsten A, Illig T, Peters A, Cauchi S, Sladek R, Froguel P, Hansen T, Pedersen O, Morris AD, Palmer CN, Kathiresan S, Melander O, Nilsson PM, Groop LC, Barroso I, Langenberg C, Wareham NJ, O'Callaghan CA, Gloyn AL, Altshuler D, Boehnke M, Teslovich TM, McCarthy MI, Morris AP; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. Nat Genet. 2015 Dec;47(12):1415-25.

Genetic Predisposition to Polycystic Ovary Syndrome, Postpartum Weight Reduction, and Glycemic Changes: A Longitudinal Study in Women With Prior Gestational Diabetes. Wang T, Leng J, Li N, Martins de Carvalho A, Huang T, Zheng Y, Li W, Liu H, Wang L, Hu G, Qi L. J Clin Endocrinol Metab. 2015 Dec;100(12):E1560-7.

Vitamin D metabolism-related genetic variants, dietary protein intake and improvement of insulin resistance in a 2 year weight-loss trial: POUNDS Lost. Qi Q, Zheng Y, Huang T, Rood J, Bray GA, Sacks FM, Qi L. Diabetologia. 2015 Dec;58(12):2791-9.

DNA Methylation Variants at HIF3A Locus, B-Vitamin Intake, and Long-term Weight Change: Gene-Diet Interactions in Two U.S. Cohorts. Huang T, Zheng Y, Qi Q, Xu M, Ley SH, Li Y, Kang JH, Wiggs J, Pasquale LR, Chan AT, Rimm EB, Hunter DJ, Manson JE, Willett WC, Hu FB, Qi L. Diabetes. 2015 Sep;64(9):3146-54

Neuropeptide Y genotype, central obesity, and abdominal fat distribution: the POUNDS LOST trial. Lin X, Qi Q, Zheng Y, Huang T, Lathrop M, Zelenika D, Bray GA, Sacks FM, Liang L, Qi L. Am J Clin Nutr. 2015 Aug;102(2):514-9