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APPLIED MALARIA RESEARCH & EVALUATION

Evidence that moves malaria programs forward.

CAMRE works alongside ministries of health, researchers, and global partners to answer the operational questions that shape malaria control and elimination.

Explore our projects

Photograph of two people standing inside a hut with a thatched roof, inspecting the walls.


FEATURED RESEARCH 2024

Estimating infectious bites across communities

Community estimates combine human behavior and mosquito measurements to compare potential malaria exposure among net users and nonusers in western Zambia.

Read the publication

 


 

  • 2013

    CAMRE established

  • 10+

    Countries reached by our research

  • 150+

    Evidence-based publications


| Measure malaria burden |
 


| Evaluate interventions |
 


| Strengthen surveillance |
 


| Translate evidence |
 

ABOUT CAMRE

Applied research at the intersection of science and implementation

 

 

CAMRE is based in the Department of Tropical Medicine and Infectious Disease at Tulane University's Celia Scott Weatherhead School of Public Health and Tropical Medicine. We generate evidence that helps malaria programs select, target, deliver, and evaluate interventions in real-world settings.

Our work links epidemiology, health economics, geospatial analysis, implementation science, vector control, social science, and program evaluation—bringing the right methods to the decisions partners need to make.
 

Our Mission

Build a practical evidence base for malaria control and elimination while strengthening the ability of researchers and programs in malaria-endemic settings to generate and use that evidence.

WHAT WE DO
 

Capabilities across the evidence cycle

CAMRE teams move from defining the problem to generating evidence, supporting implementation, and communicating findings for policy and practice.
 

01 — Epidemiology and transmission 


Measuring malaria burden, transmission patterns, risk factors, and population-level outcomes.

02 — Impact evaluation 


Designing rigorous evaluations of programs and interventions under real-world conditions.

03 — Surveillance and analytics 


Improving routine information systems, geospatial analysis, risk mapping, and data use.

04 — Vector control research 


Evaluating established and next-generation tools, including delivery, coverage, and durability.

05 — Economics and optimization 


Assessing costs, cost-effectiveness, resource allocation, and the value of alternative strategies.

06 — Implementation and behavior 


Studying feasibility, acceptability, use, and the systems that turn interventions into impact.

 


 

FEATURED PROJECT

2026–2027 · Zambia · Ethiopia

SPEED-UP 

Spatial Emanator Evidence Generation for Delivery and Uptake


A multi-country implementation and evaluation project examining how spatial emanators perform under real-world malaria-control conditions.

Led by Tulane in partnership with IVCC, Akros Inc., Jimma University, and national malaria programs, SPEED-UP combines malaria prevalence and household surveys, routine surveillance and coverage analysis, 12-month product durability monitoring, mosquito collections, and bioefficacy testing. The evidence will support national decisions and global policy on effectiveness, cost-effectiveness, coverage, durability, acceptability, and programmatic use.

Project leads
Joshua Yukich and Ruth Ashton 
Country partners
Akros Inc. and Jimma University 
Core evidence
Epidemiology · Entomology · Economics · Implementation

Study Components
 

  • Baseline and endline prevalence surveys 
  • Routine surveillance and geospatial analysis
  • Coverage and 12-month durability monitoring 
  • Baseline, post-deployment, and endline mosquito collections 
  • Spatial emanator bioefficacy testing 
  • Cost and cost-effectiveness analysis

RESEARCH PORTFOLIO

Ongoing and completed research  

Following SPEED-UP, explore other CAMRE projects connecting rigorous methods with the operational needs of malaria programs and partners.

 

SENSE Trial — Ongoing 2026–2028 · Uganda 


The Spatial Emanators / Indoor Residual Spraying Evaluation is a three-arm cluster-randomized malaria trial sponsored by Pilgrim Africa. CAMRE provides independent statistical and health-economic support, including randomization, analysis planning, primary endpoint analysis, costing, and cost-effectiveness analysis. 

Focus: Spatial emanators and malaria prevention

SENSE Trial
2026-2028 
Uganda
 


Spatial Emanators / Indoor Residual Spraying Evaluation (SENSE) is a three-arm cluster-randomized malaria trial sponsored by Pilgrim Africa. 

Focus: health economic support and analysis

PMI Insights 
Completed 2020–2025 
Multi-country 
 


Generating evidence to address critical gaps in malaria-control policy, strategy, and implementation guidance. 

Focus: Evidence for policy and programs

PMI Measure Malaria 
Completed 2019–2025 
Multi-country 
 


Strengthening malaria information systems and developing methods and tools to address priority health information challenges. 

Focus: Surveillance and data use

Attractive Targeted Sugar Baits 
Completed 2018–2024 
Zambia · Mali · Kenya 


Evaluating a novel vector-control tool through community-randomized trials, including malaria outcomes and field delivery.

Focus: Next-generation vector control

Additional Areas of Work 


Mass drug administration; Next-generation insecticide-treated nets; Epidemic detection systems; Cost-effectiveness; Population surveys; Capacity strengthening.

All CaMRE Projects

 


 

FEATURED RESEARCH INSIGHT 

Peer-reviewed evidence · 2024

Four line graphs labeled A, B, C, and D showing data by age groups and hours.

Children’s nighttime activities and mosquito biting patterns in Western Province, Zambia. Source: Ashton et al. (2024), Figure 1.

View a larger version of this figure ↗ 

PERSISTENT TRANSMISSION 

Why can malaria transmission persist even when bed-net coverage is high?

Protection depends not only on whether a household owns a net, but also on when children are indoors, when they are under a net, and when malaria mosquitoes bite.

CAMRE researchers interview-reported nighttime activities with indoor and outdoor mosquito-landing patterns. The analysis helps identify the hours when exposure can remain—and where additional vector-control tools may close the gap. 

Setting
Western Province, Zambia
Evidence
Human behavior + entomology
Study data
2021–2023

 

Interdisciplinary by design
 

Selected CAMRE leadership and researchers bring expertise across epidemiology, economics, surveillance, vector control, social science, and implementation.

Thom Eisele, PhD, MPH Director 
Malaria epidemiology and impact evaluation 

Ruth Ashton, PhD 
Epidemiology, surveillance, and implementation research 

Joshua Yukich, PhD 
Epidemiology, health economics, and vector control 

Kristin Banek, PhD 
Malaria programs, treatment, and implementation 

Joe Keating, PhD 
Malaria and vector-borne disease epidemiology 

Paul Hutchinson, PhD 
Health economics and program impact evaluation 

Katherine Andrinopoulos, PhD 
Implementation research and social science 

Yazoume Ye, PhD 
Surveillance, monitoring, and data for decision-making

FEATURED PUBLICATIONS 

Selected publications from CAMRE research

Recent peer-reviewed work across service delivery, vector control, surveillance, and program effectiveness. Select a paper to read the full publication.

AJTMH · 2024 

 

Trials · 2023

 

Malaria Journal · 2023

 

Can outreach training and supportive supervision improve competency in malaria service delivery? Evaluation across Cameroon, Ghana, Niger, and Zambia. 

Read the paper ↗ 

Master statistical analysis plan for attractive targeted sugar bait phase III trials Multi-site trials in Kenya, Mali, and Zambia. 

Read the paper ↗ 

Effectiveness of community case management on severe malaria and inpatient malaria deaths A dose-response study using routine health information system data in Zambia. 

Read the paper ↗ 

PARTNER WITH CAMRE 

Bring us the decision your program needs to make.

We welcome conversations with research collaborators, funders, ministries of health, implementers, and institutions seeking rigorous applied malaria research and evaluation. 

Research and partnership inquiries