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Department of Tropical Medicine Seminar Series: Differential Regulation of Innate Antiviral Immunity

Online

Featuring Kislay Parvatiyar, Ph.D. Assistant Professor (TU)

Photo of Dr. Kislay Parvatiyar

The induction of type I interferon cytokines (IFN-I) plays an essential role in innate antiviral immunity by suppressing virus replication and spread. Upon virus infection, cells of the immune system utilize germ-line encoded pattern recognition receptors to detect viral genomes which trigger the activation of IFN-I. Here we describe how a disparate signaling pathway primarily involved in lymphoid organogenesis and B-cell homeostasis, differentially regulates the IFN-I response during RNA and DNA viral infections.

Online: https://tulane.zoom.us/j/93873115349