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Diarrheal diseases are the second leading cause of death in children under five. Developing effective parenterally (non-mucosally) delivered vaccines targeted to combat mucosal infections is essential. We show that intradermal immunization with non-toxic double-mutant heat-labile toxin (dmLT) drives endogenous, antigen-specific CD4+ T cells to expand and migrate into the intestines. We also find dmLT produces a balanced Th1, Th2, and Th17 response.

With Dr. Peter Agre, Nobel Laureate in Chemistry & Director of Johns Hopkins Malaria Research Institute in Diboll Auditorium, with reception to follow in Gallery. Email nkumar@tulane.edu for more info.

With Dr.

With Joseph Keating, DTM.

With Dr Natthida Petchampai Postdoctoral fellow, TU.

Presented by Marissa Fahlberg, Ph.D. student

Presented by Thom Eisele, PhD. 1:00pm, Room 504 JBJ

 

Dr. Michael Behnke Assistant Professor, LSU, discusses “Amplified virulence determinants and enteric stage development of the intracellular parasite Toxoplasma gondii.”

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